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Salesforce Unveils Agentforce 360 and Expands OpenAI, Anthropic Partnerships

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Salesforce began the first day of its annual Dreamforce event in San Francisco on October 14, 2025, with a series of major announcements that mark a defining moment for enterprise artificial intelligence. The company unveiled Agentforce 360, a platform representing a full transformation of Salesforce into what CEO Marc Benioff calls the Agentic Enterprise. At the same time, Salesforce revealed expanded strategic partnerships with OpenAI and Anthropic, positioning its ecosystem at the forefront of responsible, enterprise-grade AI adoption.

According to new research from IDC and Salesforce, 67 percent of Canadian and American CEOs view AI agents as critical to staying competitive. With business leaders facing productivity challenges, global trade instability, and complex workforce transitions, Salesforce’s announcements offer a path to efficiency, trust, and innovation.

“We’re entering the age of the Agentic Enterprise — where AI elevates human potential like never before,” said Marc Benioff, Chair and CEO of Salesforce. “Agentforce 360 connects humans, agents, and data on one trusted platform, helping every employee and every company achieve more than they ever thought possible.”

Marc Benioff, Chair and CEO of Salesforce

The Launch of Agentforce 360

Agentforce 360 marks the culmination of a year of transformation for Salesforce. While many companies are still exploring what AI agents can do, Salesforce has spent the past year delivering on the promise of agentic AI, with four major releases and thousands of enterprise deployments.

This evolution has redefined how work gets done across organizations. Within the Agentic Enterprise, AI does not replace employees but enhances them, ensuring sales leads are never missed, service operates continuously, and every team member benefits from an AI partner that supports decision-making, problem-solving, and execution in real time.

Over the last twelve months, Salesforce introduced several milestones that paved the way for Agentforce 360:

  • Agentforce (October 2024): The first enterprise AI agent platform.
  • Agentforce 2 (December 2024): Enhanced reasoning engine for grounded, predictable results.
  • Agentforce 2dx (March 2025): Enabled agents to integrate across workflows and functions.
  • Agentforce 3 (June 2025): Introduced interoperability and governance at enterprise scale.

These innovations culminate in Agentforce 360, a platform that extends Salesforce beyond CRM, transforming how businesses sell, serve, and collaborate.

A Platform Built on Trust

Salesforce emphasized that the foundation of Agentforce 360 rests on its 26-year legacy of trust and reliability. The technology powering the company’s CRM, analytics, and automation systems now fuels AI agents capable of turning every workflow into intelligent action.

Agentforce 360 integrates four critical components that define the Agentic Enterprise:

  • Agentforce 360 Platform: A foundation for enterprise-grade AI agents, featuring a conversational builder, hybrid reasoning capabilities for precision and control, and integrated voice technology.
  • Data 360: A unified, trusted data layer that provides contextual understanding through innovations such as Intelligent Context and Tableau Semantics.
  • Customer 360 Apps: Applications that embed institutional knowledge and business logic, now reimagined with AI agents that understand every customer and process in depth.
  • Slack: A real-time collaboration layer connecting humans and agents for seamless communication and workflow management.

Together, these elements empower businesses to deploy agents that collaborate across teams, leverage trusted data, and integrate deeply within Slack and Salesforce’s existing ecosystem.

Image: Salesforce

Proven Impact Across Industries

Agentforce 360 has already demonstrated measurable success with more than 12,000 customers. Organizations across sectors are reporting transformative gains in productivity and customer experience.

For example, Reddit deflected 46 percent of support cases and cut resolution times by 84 percent. “This efficiency lets us provide on-demand help for complex tasks, boost advertiser satisfaction by 20 percent, and free up human reps from repetitive questions,” said John Thompson, Vice President of Sales Strategy and Operations.

At Adecco, AI agents handled 51 percent of candidate conversations outside of regular business hours. “Agentforce lets us automate high-volume tasks, strategically freeing our recruiters’ time to focus on quality customer engagement,” said Pierre Matuchet, Senior Vice President of IT and Digital Transformation.

OpenTable achieved a 70 percent autonomous resolution rate for diner and restaurant inquiries. “Agentforce delivered the warmth and white-glove service our industry demands,” said George Pokorny, Senior Vice President of Global Customer Success.

Meanwhile, Engine reduced handle time by 15 percent, saving over $2 million annually. “Its voice capabilities will let us deliver our unique brand experience directly to customers, creating trusted interactions at scale,” said CEO Elia Wallen.

Even during the busiest tax season, 1-800Accountant reached a 90 percent case deflection rate, allowing teams to focus on complex client needs.

Salesforce and OpenAI Expand Strategic Partnership

In a second announcement, Salesforce and OpenAI unveiled an expanded partnership designed to reshape both employee and consumer experiences through Salesforce’s Agentforce 360 and OpenAI’s frontier models.

This collaboration brings Agentforce 360 directly into ChatGPT, enabling users to access Salesforce data, visualize analytics with Tableau, and build prompts and agents using OpenAI’s latest GPT-5 model — all through natural conversation. The partnership also introduces a new commerce experience allowing businesses to reach hundreds of millions of potential customers within ChatGPT while maintaining full control of data and operations.

Sam Altman

“Our partnership with Salesforce is about making the tools people use every day work better together, so work feels more natural and connected,” said Sam Altman, Co-Founder and CEO of OpenAI.

Marc Benioff described the integration as a breakthrough moment: “By uniting the world’s leading frontier AI with the world’s #1 AI CRM, we’re creating the trusted foundation for companies to become Agentic Enterprises.”

Integration Across Platforms

The collaboration between Salesforce and OpenAI introduces a suite of deep integrations that make AI part of everyday work:

  • Agentforce 360 apps in ChatGPT: Users can now access Salesforce apps and Tableau visualizations directly within ChatGPT conversations.
  • Agentforce Commerce and Instant Checkout: Businesses can reach new customers within ChatGPT while managing fulfillment and customer relationships through Salesforce.
  • ChatGPT in Slack: Teams can summarize discussions, generate content, and surface insights directly within Slack channels.
  • Codex in Slack: Developers can tag Codex to write and edit code collaboratively within Slack threads, improving speed and accuracy.
  • OpenAI in Agentforce 360: Salesforce customers can select OpenAI’s GPT-5 as a default model, integrating its reasoning and multimodal capabilities directly into workflows.

This multi-surface approach bridges data and collaboration platforms, allowing teams to perform tasks, from sales forecasting to customer support, seamlessly within conversational interfaces.

Salesforce and Anthropic Strengthen Partnership for Regulated Industries

A third announcement at Dreamforce revealed a deepened partnership between Salesforce and Anthropic, focused on delivering trusted AI solutions for regulated and data-sensitive sectors such as financial services, healthcare, cybersecurity, and life sciences.

Anthropic’s Claude models are now a foundational component of the Agentforce 360 Platform. Organizations like CrowdStrike and RBC Wealth Management are already using Claude to develop AI-driven workflows that enhance compliance, accuracy, and productivity.

“Salesforce and Anthropic share a vision for a trusted AI ecosystem that puts customers at the center,” said Benioff. “Together, we’re making trusted, agentic AI real for every industry — combining Anthropic’s world-class models with the trust, reliability, and scale of Agentforce 360.”

Anthropic’s CEO and Co-Founder, Dario Amodei, emphasized the importance of safeguards for regulated industries: “Regulated industries need frontier AI capabilities, but they also need the appropriate safeguards before they can deploy in sensitive systems. We’ve built Claude to deliver both: the performance and the safeguards.”

Dario Amodei

Securing AI for the Enterprise

Anthropic is the first large language model provider to operate entirely within the Salesforce trust boundary, ensuring all Claude-related activity remains securely contained in Salesforce’s virtual private cloud. By combining Anthropic’s technology via Amazon Bedrock with Salesforce’s data governance standards, the partnership offers businesses in regulated sectors a secure environment to deploy AI responsibly.

For instance, RBC Wealth Management has already integrated Anthropic’s technology to assist financial advisors. “Because of Anthropic on Amazon Bedrock and Agentforce, we’re able to help our advisors with their most time-consuming task: meeting prep,” said Rohit Gupta, Head of Digital Advisor Platforms. “This has saved them significant time, allowing them to focus on what matters most – client relationships.”

A Turning Point for Enterprise AI

The launch of Salesforce Agentforce 360, along with new integrations with OpenAI and Anthropic, marks a transformative shift for enterprise software. The vision of the Agentic Enterprise, where AI agents work alongside humans in every business process, has now moved from concept to reality.

Salesforce’s focus on trust, interoperability, and responsible AI positions it as a leader in redefining digital transformation. From financial institutions and healthcare providers to technology and retail companies, the ability to deploy secure, intelligent, and conversational AI will likely shape the next era of enterprise productivity and innovation.

As Marc Benioff concluded in San Francisco, “We are not just imagining the future of work — we’re building it. With Agentforce 360, OpenAI, and Anthropic, we’re giving every company the ability to harness AI that is trusted, transformative, and human-centred.”

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Craig Patterson
Craig Patterson
Located in Toronto, Craig is the Publisher & CEO of Retail Insider Media Ltd. He is also a retail analyst and consultant, Advisor at the University of Alberta School Centre for Cities and Communities in Edmonton, former lawyer and a public speaker. He has studied the Canadian retail landscape for over 25 years and he holds Bachelor of Commerce and Bachelor of Laws Degrees.

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